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Bioengineering
Clinical Biomedical Engineering

The cryopreservation of organized, mammalian tissues is a challenging task as opposed to cells in suspension. The main issue is that connective tissues succumb to damage as a result of uncontrolled ice growth in the tissue matrix. From an engineering standpoint, connective tissues can be viewed as a charged, organic extracellular matrix infused with an ionic interstitial fluid. Our objective is to study ice growth, its structure and the osmotic environment that it creates in the tissue matrix. A mathematical model that can predict cellular injury given information about the tissue morphology, ice structure and osmotic environment within connective tissues will be developed.

More about Tissue Cryo-Engineering

A rapidly growing area of biomedical engineering is in the use of inhaled aerosols to deliver drugs for the treatment and prevention of disease. Inhaled aerosols are being developed for such diverse applications as pain management, treating diseases such as diabetes, cystic fibrosis and asthma, as well as vaccination against flus and other viruses.

The mechanics and physics of aerosol delivery remains poorly understood because of the complex physical processes involved and the complex geometry of the respiratory tract. The Aerosol Research Laboratory at the University of Alberta is a world renowned facility dedicated to research in this field.